产品详情
简单介绍:
Human NRGN/Neurogranin protein (Recombinant) (C-hFC) (STJP001978)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human NRGN/Neurogranin-C-hFC protein was developed from hek293 cells and has a target region of C-hFC. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of 20mM Tris 150mM Nacl, pH 7.5. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | NRGN |
Gene ID: | 4900 |
Uniprot ID: | NEUG_HUMAN |
Immunogen Region: | Asp2-Asp78 |
Immunogen: | Recombinant Human NRGN/Neurogranin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp2-Asp78) of human NRGN/Neurogranin (Accession #) fused with hFc tag at the C-terminus. |
Post Translational Modifications | Phosphorylated at Ser-36 by PHK and PKC, phosphorylation prevents interaction with Calmodulin and interrupts several learning- and memory-associated functions. |
Function | Acts as a 'third messenger' substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium. |
Protein Name | Neurogranin Ng Rc3 Cleaved Into - Neug(55-78 |
Database Links | Reactome: R-HSA-9620244 |
Alternative Protein Names | Neurogranin protein Ng protein Rc3 Cleaved Into - Neug(55-78 protein NRGN protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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