产品详情

  • 产品名称：Human PDGF-BB protein (Recombinant) (No-tag) (STJP001936)

  • 产品型号：STJP001936
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human PDGF-BB protein (Recombinant) (No-tag) (STJP001936)
详情介绍：
Host: Pichia
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human PDGF-BB-No-tag protein was developed from pichia and has a target region of No-tag. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of 20mM NaAc, pH 4.5.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Measured by its binding ability in a functional ELISA.Immobilized PDGF-BB (Catalog: RP01763) at 2 Mu g/mL (100 Mu L/well) can bind Human PDGFRB (Catalog: RP00126) with a linear range of 0.1-104.7 ng/mL.
Gene Symbol: PDGFB
Gene ID: 5155
Uniprot ID: PDGFB_HUMAN
Immunogen Region: Ser82-Thr190
Immunogen: Recombinant Human PDGF-BB Protein is produced by Pichia expression system. The target protein is expressed with sequence (Ser82-Thr190) of human PDGF-BB (Accession #NP_002599.1) fused with a additional amino acid free.
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.
Protein Name Platelet-Derived Growth Factor Subunit B
Pdgf Subunit B
Pdgf-2
Platelet-Derived Growth Factor B Chain
Platelet-Derived Growth Factor Beta Polypeptide
Proto-Oncogene C-Sis
Becaplermin
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-1257604
Reactome: R-HSA-186763
Reactome: R-HSA-186797
Reactome: R-HSA-2219530
Reactome: R-HSA-3000171
Reactome: R-HSA-5673001
Reactome: R-HSA-6811558
Cellular Localisation Secreted
Released By Platelets Upon Wounding
Alternative Protein Names Platelet-Derived Growth Factor Subunit B protein
Pdgf Subunit B protein
Pdgf-2 protein
Platelet-Derived Growth Factor B Chain protein
Platelet-Derived Growth Factor Beta Polypeptide protein
Proto-Oncogene C-Sis protein
Becaplermin protein
PDGFB protein
PDGF2 protein
SIS protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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