产品详情
简单介绍:
Human PSMA/FOLH1 protein (Recombinant) (N-hFc) (STJP002392)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human PSMA/FOLH1-N-hFc protein was developed from hek293 cells and has a target region of N-hFc. For use in research applications. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FOLH1 |
Gene ID: | 2346 |
Uniprot ID: | FOLH1_HUMAN |
Immunogen Region: | Lys44-Ala750 |
Immunogen: | Recombinant Human PSMA/FOLH1 Protein is expressed from Expi293 with hFc tag at the N-terminal.;It contains Lys44-Ala750. |
Post Translational Modifications | The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked. |
Function | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. |
Protein Name | Glutamate Carboxypeptidase 2 Cell Growth-Inhibiting Gene 27 Protein Folate Hydrolase 1 Folylpoly-Gamma-Glutamate Carboxypeptidase Fgcp Glutamate Carboxypeptidase Ii Gcpii Membrane Glutamate Carboxypeptidase Mgcp N-Acetylated-Alpha-Linked Acidic Dipeptidase I Naaladase I Prostate-Specific Membrane Antigen Psm Psma Pteroylpoly-Gamma-Glutamate Carboxypeptidase |
Database Links | Reactome: R-HSA-8963693 |
Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein Isoform Psma': Cytoplasm |
Alternative Protein Names | Glutamate Carboxypeptidase 2 protein Cell Growth-Inhibiting Gene 27 Protein protein Folate Hydrolase 1 protein Folylpoly-Gamma-Glutamate Carboxypeptidase protein Fgcp protein Glutamate Carboxypeptidase Ii protein Gcpii protein Membrane Glutamate Carboxypeptidase protein Mgcp protein N-Acetylated-Alpha-Linked Acidic Dipeptidase I protein Naaladase I protein Prostate-Specific Membrane Antigen protein Psm protein Psma protein Pteroylpoly-Gamma-Glutamate Carboxypeptidase protein FOLH1 protein FOLH protein NAALAD1 protein PSM protein PSMA protein GIG27 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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