产品详情

  • 产品名称：Human Thrombospondin-5/COMP protein (Recombinant) (C-His) (STJP001026)

  • 产品型号：STJP001026
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Human Thrombospondin-5/COMP protein (Recombinant) (C-His) (STJP001026)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Thrombospondin-5/COMP-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Gene Symbol: COMP
Gene ID: 1311
Uniprot ID: COMP_HUMAN
Immunogen: Recombinant Human Thrombospondin-5/COMP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln 21-Ala 757 ) of human COMP (Accession #NP_000086.2) fused with a 6×His tag at the C-terminus.
Function Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7.
Protein Name Cartilage Oligomeric Matrix Protein
Comp
Thrombospondin-5
Tsp5
Database Links Reactome: R-HSA-216083
Reactome: R-HSA-3000178
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Cartilage Oligomeric Matrix Protein protein
Comp protein
Thrombospondin-5 protein
Tsp5 protein
COMP protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 
网站地图