产品详情

  • 产品名称：Human TIGIT protein (Recombinant) (C-His) (STJP000856)

  • 产品型号：STJP000856
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human TIGIT protein (Recombinant) (C-His) (STJP000856)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human TIGIT-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human TIGIT at 1.5 Mu g/mL (100 Mu L/well) can bind Human CD155 with a linear range of 0.15-1.2 Mu g/mL.
Gene Symbol: TIGIT
Gene ID: 201633
Uniprot ID: TIGIT_HUMAN
Immunogen Region: Met22-Pro141
Immunogen: Recombinant Human TIGIT Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met22-Pro141) of human TIGIT (Accession #NP_776160.2) fused with a 6×His tag at the C-terminus.
Tissue Specificity Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level).
Function Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Protein Name T-Cell Immunoreceptor With Ig And Itim Domains
V-Set And Immunoglobulin Domain-Containing Protein 9
V-Set And Transmembrane Domain-Containing Protein 3
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names T-Cell Immunoreceptor With Ig And Itim Domains protein
V-Set And Immunoglobulin Domain-Containing Protein 9 protein
V-Set And Transmembrane Domain-Containing Protein 3 protein
TIGIT protein
VSIG9 protein
VSTM3 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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