产品详情

  • 产品名称：Anti-AQP3 antibody (178-292) (STJ22660)

  • 产品型号：STJ22660
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-AQP3 antibody (178-292) (STJ22660)
详情介绍：
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AQP3 (178-292) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AQP3
Gene ID: 360
Uniprot ID: AQP3_HUMAN
Immunogen Region: 178-292
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 178-292 of human AQP3 (NP_004916.1).
Immunogen Sequence: IVDPYNNPVPRGLEAFTVGL VVLVIGTSMGFNSGYAVNPA RDFGPRLFTALAGWGSAVFT TGQHWWWVPIVSPLLGSIAG VFVYQLMIGCHLEQPPPSNE EENVKLAHVKHKEQI
Tissue Specificity Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.
Function Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
Protein Name Aquaporin-3
Aqp-3
Aquaglyceroporin-3
Database Links Reactome: R-HSA-432040
Reactome: R-HSA-432047
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Alternative Antibody Names Anti-Aquaporin-3 antibody
Anti-Aqp-3 antibody
Anti-Aquaglyceroporin-3 antibody
Anti-AQP3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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