产品详情

  • 产品名称：Anti-ANAPC11 antibody (Internal) (STJ72106)

  • 产品型号：STJ72106-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ANAPC11 antibody (Internal) (STJ72106)
详情介绍：
Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ANAPC11 (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.3-1µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ANAPC11
Gene ID: 51529
Uniprot ID: APC11_HUMAN
Immunogen Region: Internal
Accession Number: NP_001002244.1; NP_057560.8
Specificity: This antibody is expected to recognize. Reported variants represent identical protein: NP_057560.8, NP_001002248.1, NP_001002245.1, NP_001002246.1, NP_001002247.1, NP_001002249.1
Immunogen Sequence: PALDQETSSLLRCTS
Post Translational Modifications Auto-ubiquitinated.
Function Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
Protein Name Anaphase-Promoting Complex Subunit 11
Apc11
Cyclosome Subunit 11
Hepatocellular Carcinoma-Associated Ring Finger Protein
Database Links Reactome: R-HSA-141430
Reactome: R-HSA-174048
Reactome: R-HSA-174084
Reactome: R-HSA-174154
Reactome: R-HSA-174178
Reactome: R-HSA-174184
Reactome: R-HSA-176407
Reactome: R-HSA-176408
Reactome: R-HSA-176409
Reactome: R-HSA-176412
Reactome: R-HSA-179409
Reactome: R-HSA-2467813
Reactome: R-HSA-2559582
Reactome: R-HSA-68867
Reactome: R-HSA-69017
Reactome: R-HSA-8853884
Reactome: R-HSA-9687136
Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Anaphase-Promoting Complex Subunit 11 antibody
Anti-Apc11 antibody
Anti-Cyclosome Subunit 11 antibody
Anti-Hepatocellular Carcinoma-Associated Ring Finger Protein antibody
Anti-ANAPC11 antibody
Anti-HSPC214 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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