产品详情
简单介绍:
Anti-BAG5 antibody (30-110 aa) (STJ96426)
详情介绍:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-BAG family molecular chaperone regulator 5 (30-110 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 ELISA 1:5000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | BAG5 |
Gene ID: | 9529 |
Uniprot ID: | BAG5_HUMAN |
Immunogen Region: | 30-110 aa |
Specificity: | BAGE5 Polyclonal Antibody detects endogenous levels of BAGE5 protein. |
Immunogen: | Synthesized peptide derived from BAGE5 at the amino acid range 30-110 |
Function | Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding. Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN. |
Protein Name | Bag Family Molecular Chaperone Regulator 5 Bag-5 Bcl-2-Associated Athanogene 5 |
Database Links | Reactome: R-HSA-3371453 |
Cellular Localisation | In Cardiomyocytes Localized At Specialized Membrane Contact Sites Between T-Tubules And The Sarcoplasmic Reticulum Known As Junctional Membrane Complexes |
Alternative Antibody Names | Anti-Bag Family Molecular Chaperone Regulator 5 antibody Anti-Bag-5 antibody Anti-Bcl-2-Associated Athanogene 5 antibody Anti-BAG5 antibody Anti-KIAA0873 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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