产品详情
简单介绍:
Human FRZB (Frizzled Related Protein) Sandwich ELISA Kit Ready-To-Use (STJE0015359)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 12.9pg/mL |
Detection Limit: | 31.2-2000pg/mL |
Short Description: | This FRZB Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | FRZB |
Gene ID: | 2487 |
Uniprot ID: | SFRP3_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma or other biological fluids. |
Tissue Specificity | Expressed primarily in the cartilaginous cores of the long bone during embryonic and fetal development and in the appendicular skeleton (6-13 weeks). At 13 weeks of gestation, transcripts were present in early chondroblasts of the tarsal bones of the foot, the carpal bones of the hands and the epiphysis of long bones. Highly expressed in placenta and heart, followed by brain, skeletal muscle, kidney and pancreas. Weakly expressed in lung and liver. |
Post Translational Modifications | |
Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development. |
Protein Name | Secreted Frizzled-Related Protein 3 Sfrp-3 Frezzled Fritz Frizzled-Related Protein 1 Frzb-1 |
Database Links | |
Cellular Localisation | Secreted |
Alternative ELISA Names | Secreted Frizzled-Related Protein 3 ELISA kit Sfrp-3 ELISA kit Frezzled ELISA kit Fritz ELISA kit Frizzled-Related Protein 1 ELISA kit Frzb-1 ELISA kit FRZB ELISA kit FIZ ELISA kit FRE ELISA kit FRP ELISA kit FRZB1 ELISA kit SFRP3 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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