产品详情

  • 产品名称：Anti-BPI antibody (248-487) (STJ27291)

  • 产品型号：STJ27291
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-BPI antibody (248-487) (STJ27291)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BPI (248-487) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BPI
Gene ID: 671
Uniprot ID: BPI_HUMAN
Immunogen Region: 248-487
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 248-487 of human BPI (NP_001716.2).
Immunogen Sequence: AETLDVQMKGEFYSENHHNP PPFAPPVMEFPAAHDRMVYL GLSDYFFNTAGLVYQEAGVL KMTLRDDMIPKESKFRLTTK FFGTFLPEVAKKFPNMKIQI HVSASTPPHLSVQPTGLTFY PAVDVQAFAVLPNSSLASLF LIGMHTTGSMEVSAESNRLV GELKLDRLLLELKHSNIGPF PVELLQDIMNYIVPILVLPR VNEKLQKGFPLPTPARVQLY NVVLQPHQNFLLFGADVVY
Tissue Specificity Restricted to cells of the myeloid series.
Function The cytotoxic action of BPI is limited to many species of Gram-negative bacteria.this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Protein Name Bactericidal Permeability-Increasing Protein
Bpi
Cap 57
Database Links Reactome: R-HSA-166016
Reactome: R-HSA-6798695
Reactome: R-HSA-6803157
Cellular Localisation Secreted
Cytoplasmic Granule Membrane
Membrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules
Alternative Antibody Names Anti-Bactericidal Permeability-Increasing Protein antibody
Anti-Bpi antibody
Anti-Cap 57 antibody
Anti-BPI antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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