产品详情

  • 产品名称：Human FUT6 (Fucosyltransferase 6) Sandwich ELISA Kit Ready-To-Use (STJE0015389)

  • 产品型号：STJE0015389
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human FUT6 (Fucosyltransferase 6) Sandwich ELISA Kit Ready-To-Use (STJE0015389)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.65ng/mL
Detection Limit: 1.56-100ng/mL
Short Description: This FUT6 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: FUT6
Gene ID: 2528
Uniprot ID: FUT6_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Kidney, liver, colon, small intestine, bladder, uterus and salivary gland.
Post Translational Modifications N-glycosylated. Proteolytic cleavage releases a secreted glycoform of 43 kDa.
Function Isoform 1: Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine unit of a glycoprotein- or a glycolipid-linked sialopolylactosamines chain or of a distal or internal lactosamine unit of a neutral glycoprotein- or a glycolipid-linked polylactosamines chain through an alpha-1,3 glycosidic linkage and participates in surface expression of the sialyl Lewis X (sLe(x)), Lewis X (Le(x)) and non sialylated VIM2 determinants. Moreover transfers fucose to H-type 2 (Fucalpha1-2Galbeta1-4GlcNAc) chain acceptor substrates and participates in difucosylated sialyl Lewis x determinants. Also fucosylates a polylactosamine substrate having a 6 sulfate modification at the GlcNAc moiety and gives rise to sialyl and non-sialyl 6-sulfo lewis X. Does not have activity towards type 1 ((Galbeta1-3GlcNAc)) and H-type 1 chain (Fucalpha1-2Galbeta1-3GlcNAc) acceptors substrates. Isoform 2: Does not have alpha(1,3)-fucosyltransferase activity.
Protein Name 4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase Fut6
Fucosyltransferase 6
Fucosyltransferase Vi
Fuc-Tvi
Fuct-Vi
Galactoside 3-L-Fucosyltransferase
Database Links Reactome: R-HSA-9037629
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Membrane-Bound Form In Trans Cisternae Of Golgi
Alternative ELISA Names 4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase Fut6 ELISA kit
Fucosyltransferase 6 ELISA kit
Fucosyltransferase Vi ELISA kit
Fuc-Tvi ELISA kit
Fuct-Vi ELISA kit
Galactoside 3-L-Fucosyltransferase ELISA kit
FUT6 ELISA kit
FCT3A ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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