产品详情
简单介绍:
Anti-B56 beta isoform-Isoform Beta antibody (C-Term) (STJ70086)
详情介绍:
Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-B56 beta isoform-Isoform Beta (C-Term) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-2-3µg/ml ELISA-antibody detection limit dilution 1:2000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | PPP2R5B |
Gene ID: | 5526 |
Uniprot ID: | 2A5B_HUMAN |
Immunogen Region: | C-Term |
Accession Number: | NP_006235.1 |
Immunogen Sequence: | QRLTPQVAASGGQS |
Post Translational Modifications | Ubiquitinated by E3 CUL3-KLHL15 complex.this modification leads to proteasomal degradation. |
Function | As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation. |
Protein Name | Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Beta Isoform Pp2a B Subunit Isoform B'-Beta Pp2a B Subunit Isoform B56-Beta Pp2a B Subunit Isoform Pr61-Beta Pp2a B Subunit Isoform R5-Beta |
Database Links | Reactome: R-HSA-141444 Reactome: R-HSA-195253 Reactome: R-HSA-196299 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-381038 Reactome: R-HSA-389513 Reactome: R-HSA-432142 Reactome: R-HSA-4641262 Reactome: R-HSA-5339716 Reactome: R-HSA-5358747 Reactome: R-HSA-5358749 Reactome: R-HSA-5358751 Reactome: R-HSA-5358752 Reactome: R-HSA-5467337 Reactome: R-HSA-5467340 Reactome: R-HSA-5467348 Reactome: R-HSA-5663220 Reactome: R-HSA-5673000 Reactome: R-HSA-5675221 Reactome: R-HSA-6811558 Reactome: R-HSA-68877 Reactome: R-HSA-9648025 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Beta Isoform antibody Anti-Pp2a B Subunit Isoform B'-Beta antibody Anti-Pp2a B Subunit Isoform B56-Beta antibody Anti-Pp2a B Subunit Isoform Pr61-Beta antibody Anti-Pp2a B Subunit Isoform R5-Beta antibody Anti-PPP2R5B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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