产品详情
简单介绍:
Anti-CD10 antibody [ZR329] (STJ180490)
详情介绍:
Host: | Rabbit |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-CD10 is suitable for use in Immunohistochemistry research applications. |
Clonality: | Monoclonal |
Clone ID: | ZR329 |
Conjugation: | Unconjugated |
Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% proclin<="" td=""> 0.1%> |
Purification: | Affinity purified |
Dilution Range: | 1:100-200 |
Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Gene Symbol: | MME |
Gene ID: | 4311 |
Uniprot ID: | NEP_HUMAN |
Post Translational Modifications | Myristoylation is a determinant of membrane targeting. Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity. |
Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
Protein Name | Neprilysin Atriopeptidase Common Acute Lymphocytic Leukemia Antigen Calla Enkephalinase Neutral Endopeptidase 24.11 Nep Neutral Endopeptidase Skin Fibroblast Elastase Sfe Cd Antigen Cd10 |
Database Links | Reactome: R-HSA-2022377 Reactome: R-HSA-5578768 Reactome: R-HSA-6798695 |
Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Neprilysin antibody Anti-Atriopeptidase antibody Anti-Common Acute Lymphocytic Leukemia Antigen antibody Anti-Calla antibody Anti-Enkephalinase antibody Anti-Neutral Endopeptidase 24.11 antibody Anti-Nep antibody Anti-Neutral Endopeptidase antibody Anti-Skin Fibroblast Elastase antibody Anti-Sfe antibody Anti-Cd Antigen Cd10 antibody Anti-MME antibody Anti-EPN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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