产品详情
简单介绍:
Human LECT1 (Leukocyte Cell Derived Chemotaxin 1) Sandwich ELISA Kit Ready-To-Use (STJE0016685)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.051ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This LECT1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | CNMD |
Gene ID: | 11061 |
Uniprot ID: | CNMD_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosesa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma. |
Post Translational Modifications | After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein. |
Function | Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization. |
Protein Name | Leukocyte Cell-Derived Chemotaxin 1 Chondromodulin Cleaved Into - Chondrosurfactant Protein Ch-Sp - Chondromodulin-1 Chondromodulin-I Chm-I |
Database Links | |
Cellular Localisation | Chondromodulin-1: Secreted Extracellular Space Extracellular Matrix Accumulated In The Inter-Territorial Matrix Of Cartilage Chondrosurfactant Protein: Endomembrane System Single-Pass Membrane Protein |
Alternative ELISA Names | Leukocyte Cell-Derived Chemotaxin 1 ELISA kit Chondromodulin Cleaved Into - Chondrosurfactant Protein ELISA kit Ch-Sp - Chondromodulin-1 ELISA kit Chondromodulin-I ELISA kit Chm-I ELISA kit CNMD ELISA kit CHMI ELISA kit LECT1 ELISA kit MYETS1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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