产品详情
简单介绍:
Anti-CD200R1 antibody (29-240) (STJ11105432)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Cell Surface Glycoprotein Cd200 Receptor 1 (29-240) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CD200R1 |
Gene ID: | 131450 |
Uniprot ID: | MO2R1_HUMAN |
Immunogen Region: | 29-240 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-240 of human CD200R1 (NP_740750.1). |
Tissue Specificity | Expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells. |
Function | Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. |
Protein Name | Cell Surface Glycoprotein Cd200 Receptor 1 Cd200 Cell Surface Glycoprotein Receptor Cell Surface Glycoprotein Ox2 Receptor 1 |
Database Links | Reactome: R-HSA-198933 |
Cellular Localisation | Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 4: Cell Membrane Isoform 2: Secreted Isoform 3: Secreted |
Alternative Antibody Names | Anti-Cell Surface Glycoprotein Cd200 Receptor 1 antibody Anti-Cd200 Cell Surface Glycoprotein Receptor antibody Anti-Cell Surface Glycoprotein Ox2 Receptor 1 antibody Anti-CD200R1 antibody Anti-CD200R antibody Anti-CRTR2 antibody Anti-MOX2R antibody Anti-OX2R antibody Anti-UNQ2522 antibody Anti-PRO6015 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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