产品详情
简单介绍:
Anti-BOB1/OCAB/OBF1 antibody (C-Term) (STJ70260)
详情介绍:
Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human/Mouse/Rat/Dog/Cow |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-BOB1/OCAB/OBF1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-Recommended for use at 1-3µg/ml ELISA-antibody detection limit dilution 1:8000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | POU2AF1 |
Gene ID: | 5450 |
Uniprot ID: | OBF1_HUMAN |
Immunogen Region: | C-Term |
Accession Number: | NP_006226.2 |
Immunogen Sequence: | DAYALNHTLSVEGF |
Post Translational Modifications | Ubiquitinated.mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. |
Function | Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2. It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator. |
Protein Name | Pou Domain Class 2-Associating Factor 1 B-Cell-Specific Coactivator Obf-1 Bob-1 Oca-B Oct-Binding Factor 1 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Pou Domain Class 2-Associating Factor 1 antibody Anti-B-Cell-Specific Coactivator Obf-1 antibody Anti-Bob-1 antibody Anti-Oca-B antibody Anti-Oct-Binding Factor 1 antibody Anti-POU2AF1 antibody Anti-BOB1 antibody Anti-OBF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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