产品详情

  • 产品名称：Anti-CD54/ICAM1 antibody [15.2] {PerCP/Cyanine5.5} (STJA0002642)

  • 产品型号：STJA0002642
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CD54/ICAM1 antibody [15.2] {PerCP/Cyanine5.5} (STJA0002642)
详情介绍：
Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Intercellular adhesion molecule 1 is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: 15.2
Conjugation: PerCP/Cyanine5.5
Isotype: IgG1k
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: ICAM1
Gene ID: 3383
Uniprot ID: ICAM1_HUMAN
Post Translational Modifications Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.
Protein Name Intercellular Adhesion Molecule 1
Icam-1
Major Group Rhinovirus Receptor
Cd Antigen Cd54
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Reactome: R-HSA-877300
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 1 antibody
Anti-Icam-1 antibody
Anti-Major Group Rhinovirus Receptor antibody
Anti-Cd Antigen Cd54 antibody
Anti-ICAM1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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