产品详情

  • 产品名称：Human PROCR (Endothelial protein C receptor) CLIA Kit (STJC0000960)

  • 产品型号：STJC0000960
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human PROCR (Endothelial protein C receptor) CLIA Kit (STJC0000960)
详情介绍：
Applications: CLIA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 0.09ng/mL
Detection Limit: 0.16~10ng/mL
Short Description: This human PROCR kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Storage Instruction: If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time: 3.5h
Detection: Chemiluminescence
Gene Symbol: PROCR
Gene ID: 10544
Uniprot ID: EPCR_HUMAN
Specificity: This kit recognizes Human SEPCR/PROCR in samples. No significant cross-reactivity or interference between Human SEPCR/PROCR and analogues was observed.
Sample Type: Serum, plasma and other biological fluids
Tissue Specificity Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.
Post Translational Modifications N-glycosylated. A soluble form exists.probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
Function Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex.plays a role in the protein C pathway controlling blood coagulation.
Protein Name Endothelial Protein C Receptor
Activated Protein C Receptor
Apc Receptor
Endothelial Cell Protein C Receptor
Cd Antigen Cd201
Database Links Reactome: R-HSA-140875
Reactome: R-HSA-202733
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative CLIA Names Endothelial Protein C Receptor CLIA kit
Activated Protein C Receptor CLIA kit
Apc Receptor CLIA kit
Endothelial Cell Protein C Receptor CLIA kit
Cd Antigen Cd201 CLIA kit
PROCR CLIA kit
EPCR CLIA kit
Specificity This kit recognizes Human sEPCR in samples. No significant cross-reactivity or interference between Human sEPCR and analogues was observed.
Reproducibility Both intra-CV and inter-CV are

Information sourced from Uniprot.org


Item Specifications Storage
Micro CLIA Plate (Dismountable) 96T: 8 wells ×12 strips strips -20℃, 6 months
Reference Standard 96T: 2 vials 48T: 1 vial -20℃, 6 months
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL 60 μL -20℃, 6 months
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL 60 μL -20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL 2-8°C, 6 months
HRP Conjugate Diluent 1 vial, 14 mL 2-8°C, 6 months
Concentrated Wash Buffer (25×) 1 vial, 30 mL 2-8°C, 6 months
Substrate Reagent A 1 vial, 5 mL 2-8℃ (Protect from light)
Substrate Reagent B 1 vial, 5 mL 2-8℃ (Protect from light)
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 101-113 107
EDTA plasma(n=8) 100-114 107
Cell culture media(n=8) 85-100 92

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample 1.00 2.00 3.00 1.00 2.00 3.00
n 20.00 20.00 20.00 20.00 20.00 20.00
Mean (ng/mL) 0.50 1.52 3.49 0.52 1.50 3.52
Standard deviation 0.05 0.17 0.24 0.06 0.12 0.22
CV (%) 10.00 11.18 6.88 11.54 8.00 6.25
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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