产品详情

  • 产品名称：Anti-CDK11B antibody (10-59 aa) (STJ95104)

  • 产品型号：STJ95104
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CDK11B antibody (10-59 aa) (STJ95104)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cyclin-dependent kinase 11B (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDK11B
Gene ID: 984
Uniprot ID: CD11B_HUMAN
Immunogen Region: 10-59 aa
Specificity: PITSLRE Polyclonal Antibody detects endogenous levels of PITSLRE protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CDC2L1 at the amino acid range 10-59
Post Translational Modifications During FAS- or TNF-induced apoptosis, isoform SV9 is cleaved by caspases to produce p110C, a fragment that contains the C-terminal kinase domain. Phosphorylation at Ser-115 creates a binding site for 14-3-3 proteins. p110C can be autophosphorylated.
Function Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.
Protein Name Cyclin-Dependent Kinase 11b
Cell Division Cycle 2-Like Protein Kinase 1
Clk-1
Cell Division Protein Kinase 11b
Galactosyltransferase-Associated Protein Kinase P58/Gta
Pitslre Serine/Threonine-Protein Kinase Cdc2l1
P58 Clk-1
Database Links Reactome: R-HSA-380270
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Cyclin-Dependent Kinase 11b antibody
Anti-Cell Division Cycle 2-Like Protein Kinase 1 antibody
Anti-Clk-1 antibody
Anti-Cell Division Protein Kinase 11b antibody
Anti-Galactosyltransferase-Associated Protein Kinase P58/Gta antibody
Anti-Pitslre Serine/Threonine-Protein Kinase Cdc2l1 antibody
Anti-P58 Clk-1 antibody
Anti-CDK11B antibody
Anti-CDC2L1 antibody
Anti-CDK11 antibody
Anti-PITSLREA antibody
Anti-PK58 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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