产品详情
简单介绍:
Human RARb (Retinoic Acid Receptor Beta) Sandwich ELISA Kit Ready-To-Use (STJE0018219)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.057ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This RARb Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | RARB |
Gene ID: | 5915 |
Uniprot ID: | RARB_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expressed in aortic endothelial cells (at protein level). |
Post Translational Modifications | |
Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function. |
Protein Name | Retinoic Acid Receptor Beta Rar-Beta Hbv-Activated Protein Nuclear Receptor Subfamily 1 Group B Member 2 Rar-Epsilon |
Database Links | Reactome: R-HSA-383280 Reactome: R-HSA-5362517 Reactome: R-HSA-5617472 |
Cellular Localisation | Nucleus Cytoplasm Isoform Beta-1: Nucleus Isoform Beta-2: Nucleus Isoform Beta-4: Cytoplasm |
Alternative ELISA Names | Retinoic Acid Receptor Beta ELISA kit Rar-Beta ELISA kit Hbv-Activated Protein ELISA kit Nuclear Receptor Subfamily 1 Group B Member 2 ELISA kit Rar-Epsilon ELISA kit RARB ELISA kit HAP ELISA kit NR1B2 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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