产品详情

  • 产品名称：Anti-CENPJ antibody (510-590 aa) (STJ191681)

  • 产品型号：STJ191681
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CENPJ antibody (510-590 aa) (STJ191681)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Centromere protein J (510-590 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CENPJ
Gene ID: 55835
Uniprot ID: CENPJ_HUMAN
Immunogen Region: 510-590 aa
Specificity: CENPJ Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 510-590
Function Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner. May be involved in the control of centriolar-microtubule growth by acting as a regulator of tubulin release.
Protein Name Centromere Protein J
Cenp-J
Centrosomal P4.1-Associated Protein
Lag-3-Associated Protein
Lyst-Interacting Protein 1
Database Links Reactome: R-HSA-2565942
Reactome: R-HSA-380259
Reactome: R-HSA-380270
Reactome: R-HSA-380284
Reactome: R-HSA-380320
Reactome: R-HSA-5620912
Reactome: R-HSA-6804115
Reactome: R-HSA-8854518
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Localized Within The Center Of Microtubule Asters
During Centriole Biogenesis
It Is Concentrated Within The Proximal Lumen Of Both Parental Centrioles And Procentrioles
Alternative Antibody Names Anti-Centromere Protein J antibody
Anti-Cenp-J antibody
Anti-Centrosomal P4.1-Associated Protein antibody
Anti-Lag-3-Associated Protein antibody
Anti-Lyst-Interacting Protein 1 antibody
Anti-CENPJ antibody
Anti-CPAP antibody
Anti-LAP antibody
Anti-LIP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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