产品详情

  • 产品名称：Anti-CHCHD3 antibody (1-227) (STJ11100835)

  • 产品型号：STJ11100835
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CHCHD3 antibody (1-227) (STJ11100835)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CHCHD3 (1-227) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CHCHD3
Gene ID: 54927
Uniprot ID: MIC19_HUMAN
Immunogen Region: 1-227
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human CHCHD3 (NP_060282.1).
Immunogen Sequence: MGGTTSTRRVTFEADENENI TVVKGIRLSENVIDRMKESS PSGSKSQRYSGAYGASVSDE ELKRRVAEELALEQAKKESE DQKRLKQAKELDRERAAANE QLTRAILRERICSEEERAKA KHLARQLEEKDRVLKKQDAF YKEQLARLEERSSEFYRVTT EQYQKAAEEVEAKFKRYESH PVCADLQAKILQCYRENTHQ TLKCSALATQYMHCVNHAKQ SMLEKGG
Tissue Specificity Detected at low levels in brain, placenta, lung, liver, kidney and pancreas with increased levels in heart and skeletal muscle. Higher expression in primary lung cancers than in normal lung tissue.
Function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.
Protein Name Micos Complex Subunit Mic19
Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 3
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-8949613
Cellular Localisation Mitochondrion Inner Membrane
Lipid-Anchor
Intermembrane Side
Cytoplasm
Nucleus
Mitochondrion
Alternative Antibody Names Anti-Micos Complex Subunit Mic19 antibody
Anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 3 antibody
Anti-CHCHD3 antibody
Anti-MIC19 antibody
Anti-MINOS3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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