产品详情

  • 产品名称：Anti-CIT antibody (1000-1300) (STJ116211)

  • 产品型号：STJ116211
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CIT antibody (1000-1300) (STJ116211)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CIT (1000-1300) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CIT
Gene ID: 11113
Uniprot ID: CTRO_HUMAN
Immunogen Region: 1000-1300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1300 of human CIT (NP_001193928.1).
Immunogen Sequence: EDNAELNNQNFYLSKQLDEA SGANDEIVQLRSEVDHLRRE ITEREMQLTSQKQTMEALKT TCTMLEEQVMDLEALNDELL EKERQWEAWRSVLGDEKSQF ECRVRELQRMLDTEKQSRAR ADQRITESRQVVELAVKEHK AEILALQQALKEQKLKAESL SDKLNDLEKKHAMLEMNARS LQQKLETERELKQRLLEEQA KLQQQMDLQKNHIFRLTQGL QEALDRADLLKTERSDLEY
Function Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
Protein Name Citron Rho-Interacting Kinase
Crik
Serine/Threonine-Protein Kinase 21
Database Links Reactome: R-HSA-5625900
Reactome: R-HSA-8980692
Reactome: R-HSA-9013026
Reactome: R-HSA-9013106
Reactome: R-HSA-9013149
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Citron Rho-Interacting Kinase antibody
Anti-Crik antibody
Anti-Serine/Threonine-Protein Kinase 21 antibody
Anti-CIT antibody
Anti-CRIK antibody
Anti-KIAA0949 antibody
Anti-STK21 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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