产品详情
简单介绍:
Anti-COL25A1 antibody (NC3 region) (STJA0005756)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CLAC-P (NC3 region) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS + 0.02% NaN3 |
Purification: | Antigen Affinity Purified |
Dilution Range: | WB 1:500-1:1000 IHC ICC IP |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | COL25A1 |
Gene ID: | 84570 |
Uniprot ID: | COPA1_HUMAN |
Immunogen Region: | NC3 region |
Specificity: | Reacts with the NC3 region of human and mouse CLAC-P. |
Immunogen: | Synthetic peptide corresponding to amino acids from the NC23 region of human CLAC-P |
Post Translational Modifications | Undergoes proteolytic cleavage by furin protease to yield the soluble collagen-like Alzheimer amyloid plaque component. Glycosylated. Hydroxylated on 11% of proline residues and 49% of lysine residues. |
Function | Inhibits fibrillization of amyloid-beta peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin. |
Protein Name | Collagen Alpha-1(Xxv Chain Alzheimer Disease Amyloid-Associated Protein Amy Clac-P Cleaved Into - Collagen-Like Alzheimer Amyloid Plaque Component Clac |
Database Links | Reactome: R-HSA-1442490 Reactome: R-HSA-1650814 Reactome: R-HSA-8948216 |
Cellular Localisation | Membrane Single-Pass Type Ii Membrane Protein After Proteolytic Cleavage Clac Is Secreted |
Alternative Antibody Names | Anti-Collagen Alpha-1(Xxv Chain antibody Anti-Alzheimer Disease Amyloid-Associated Protein antibody Anti-Amy antibody Anti-Clac-P Cleaved Into - Collagen-Like Alzheimer Amyloid Plaque Component antibody Anti-Clac antibody Anti-COL25A1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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