产品详情
简单介绍:
Anti-CRHR2 antibody (71-120 aa) (STJ92475)
详情介绍:
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Corticotropin-releasing factor receptor 2 (71-120 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CRHR2 |
Gene ID: | 1395 |
Uniprot ID: | CRFR2_HUMAN |
Immunogen Region: | 71-120 aa |
Specificity: | CRF-RII Polyclonal Antibody detects endogenous levels of CRF-RII protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human CRHR2 at the amino acid range 71-120 |
Function | G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. |
Protein Name | Corticotropin-Releasing Factor Receptor 2 Crf-R-2 Crf-R2 Crfr-2 Corticotropin-Releasing Hormone Receptor 2 Crh-R-2 Crh-R2 |
Database Links | Reactome: R-HSA-373080 Reactome: R-HSA-418555 Reactome: R-HSA-422085 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Corticotropin-Releasing Factor Receptor 2 antibody Anti-Crf-R-2 antibody Anti-Crf-R2 antibody Anti-Crfr-2 antibody Anti-Corticotropin-Releasing Hormone Receptor 2 antibody Anti-Crh-R-2 antibody Anti-Crh-R2 antibody Anti-CRHR2 antibody Anti-CRF2R antibody Anti-CRH2R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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