产品详情

  • 产品名称：Anti-CTNND1 antibody (201-250 aa) (STJ94851)

  • 产品型号：STJ94851
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CTNND1 antibody (201-250 aa) (STJ94851)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Catenin delta-1 (201-250 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CTNND1
Gene ID: 1500
Uniprot ID: CTND1_HUMAN
Immunogen Region: 201-250 aa
Specificity: p120 Polyclonal Antibody detects endogenous levels of p120 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Catenin-delta1 at the amino acid range 201-250
Post Translational Modifications Phosphorylated by FER and other protein-tyrosine kinases. Phosphorylated at Ser-288 by PAK5. Dephosphorylated by PTPRJ.
Function Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.
Protein Name Catenin Delta-1
Cadherin-Associated Src Substrate
Cas
P120 Catenin
P120(Ctn
P120(Cas
Database Links Reactome: R-HSA-418990
Reactome: R-HSA-5218920
Reactome: R-HSA-8876493
Reactome: R-HSA-9762292
Reactome: R-HSA-9764302
Reactome: R-HSA-9833576
Cellular Localisation Cell Junction
Adherens Junction
Cytoplasm
Nucleus
Cell Membrane
Interaction With Glis2 Promotes Nuclear Translocations
Detected At Cell-Cell Contacts
Nanos1 Induces Its Translocations From Sites Of Cell-Cell Contact To The Cytoplasm
Cdh1 Enhances Cell Membrane Localization
Isoforms 4a And 1ab Are Excluded From The Nucleus
Isoform 1a: Nucleus
Isoform 2a: Nucleus
Isoform 3a: Nucleus
Alternative Antibody Names Anti-Catenin Delta-1 antibody
Anti-Cadherin-Associated Src Substrate antibody
Anti-Cas antibody
Anti-P120 Catenin antibody
Anti-P120(Ctn antibody
Anti-P120(Cas antibody
Anti-CTNND1 antibody
Anti-KIAA0384 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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