产品详情
简单介绍:
Anti-CYBRD1 antibody (41-91 aa) (STJ195985)
详情介绍:
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Plasma membrane ascorbate-dependent reductase CYBRD1 (41-91 aa) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CYBRD1 |
| Gene ID: | 79901 |
| Uniprot ID: | CYBR1_HUMAN |
| Immunogen Region: | 41-91 aa |
| Specificity: | This antibody detects endogenous levels of CYBR1 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human CYBR1 at the amino acid range 41-91 |
| Function | Plasma membrane reductase that uses cytoplasmic ascorbate as an electron donor to reduce extracellular Fe(3+) into Fe(2+). Probably functions in dietary iron absorption at the brush border of duodenal enterocytes by producing Fe(2+), the divalent form of iron that can be transported into enterocytes. It is also able to reduce extracellular monodehydro-L-ascorbate and may be involved in extracellular ascorbate regeneration by erythrocytes in blood. May also act as a ferrireductase in airway epithelial cells (Probable). May also function as a cupric transmembrane reductase. |
| Protein Name | Plasma Membrane Ascorbate-Dependent Reductase Cybrd1 Cytochrome B Reductase 1 Duodenal Cytochrome B Ferric-Chelate Reductase 3 |
| Database Links | Reactome: R-HSA-917937 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Apical Cell Membrane Localized At The Brush Border Of Duodenal Cells |
| Alternative Antibody Names | Anti-Plasma Membrane Ascorbate-Dependent Reductase Cybrd1 antibody Anti-Cytochrome B Reductase 1 antibody Anti-Duodenal Cytochrome B antibody Anti-Ferric-Chelate Reductase 3 antibody Anti-CYBRD1 antibody Anti-DCYTB antibody Anti-FRRS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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