产品详情

  • 产品名称：Anti-CYSLTR1 antibody (1-100) (STJ117786)

  • 产品型号：STJ117786
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CYSLTR1 antibody (1-100) (STJ117786)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CYSLTR1 (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CYSLTR1
Gene ID: 10800
Uniprot ID: CLTR1_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CYSLTR1 (NP_006630.1).
Immunogen Sequence: MDETGNLTVSSATCHDTIDD FRNQVYSTLYSMISVVGFFG NGFVLYVLIKTYHKKSAFQV YMINLAVADLLCVCTLPLRV VYYVHKGIWLFGDFLCRLST
Tissue Specificity Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart.
Function Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Protein Name Cysteinyl Leukotriene Receptor 1
Cysltr1
Cysteinyl Leukotriene D4 Receptor
Ltd4 Receptor
G-Protein Coupled Receptor Hg55
Hmtmf81
Database Links Reactome: R-HSA-391906
Reactome: R-HSA-416476
Reactome: R-HSA-9664535
Reactome: R-HSA-9679191
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Cysteinyl Leukotriene Receptor 1 antibody
Anti-Cysltr1 antibody
Anti-Cysteinyl Leukotriene D4 Receptor antibody
Anti-Ltd4 Receptor antibody
Anti-G-Protein Coupled Receptor Hg55 antibody
Anti-Hmtmf81 antibody
Anti-CYSLTR1 antibody
Anti-CYSLT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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