产品详情
简单介绍:
Anti-CYSLTR1 antibody (131-180 aa) (STJ92609)
详情介绍:
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Monkey |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Cysteinyl leukotriene receptor 1 (131-180 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CYSLTR1 |
Gene ID: | 10800 |
Uniprot ID: | CLTR1_HUMAN |
Immunogen Region: | 131-180 aa |
Specificity: | CysLTR1 Polyclonal Antibody detects endogenous levels of CysLTR1 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human CLTR1 at the amino acid range 131-180 |
Function | Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4. |
Protein Name | Cysteinyl Leukotriene Receptor 1 Cysltr1 Cysteinyl Leukotriene D4 Receptor Ltd4 Receptor G-Protein Coupled Receptor Hg55 Hmtmf81 |
Database Links | Reactome: R-HSA-391906 Reactome: R-HSA-416476 Reactome: R-HSA-9664535 Reactome: R-HSA-9679191 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Cysteinyl Leukotriene Receptor 1 antibody Anti-Cysltr1 antibody Anti-Cysteinyl Leukotriene D4 Receptor antibody Anti-Ltd4 Receptor antibody Anti-G-Protein Coupled Receptor Hg55 antibody Anti-Hmtmf81 antibody Anti-CYSLTR1 antibody Anti-CYSLT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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