产品详情

  • 产品名称：Anti-Erlin-2 antibody (50-150) [S1MR] (STJ11102711)

  • 产品型号：STJ11102711
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-Erlin-2 antibody (50-150) [S1MR] (STJ11102711)
详情介绍：
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Erlin-2 (50-150) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: S1MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERLIN2
Gene ID: 11160
Uniprot ID: ERLN2_HUMAN
Immunogen Region: 50-150
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Erlin-2 (O94905).
Immunogen Sequence: HLMLPFITSYKSVQTTLQTD EVKNVPCGTSGGVMIYFDRI EVVNFLVPNAVYDIVKNYTA DYDKALIFNKIHHELNQFCS VHTLQEVYIELFDQIDENLK L
Tissue Specificity Ubiquitous.
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex.
Protein Name Erlin-2
Endoplasmic Reticulum Lipid Raft-Associated Protein 2
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2
Spfh Domain-Containing Protein 2
Database Links Reactome: R-HSA-382556
Reactome: R-HSA-5655302
Reactome: R-HSA-5678895
Reactome: R-HSA-8853336
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Associated With Lipid Raft-Like Domains Of The Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Erlin-2 antibody
Anti-Endoplasmic Reticulum Lipid Raft-Associated Protein 2 antibody
Anti-Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2 antibody
Anti-Spfh Domain-Containing Protein 2 antibody
Anti-ERLIN2 antibody
Anti-C8orf2 antibody
Anti-SPFH2 antibody
Anti-UNQ2441 antibody
Anti-PRO5003 antibody
Anti-PRO9924 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 
网站地图