产品详情

  • 产品名称：Anti-ETV4 antibody (79-178) (STJ115799)

  • 产品型号：STJ115799
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ETV4 antibody (79-178) (STJ115799)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ETV4 (79-178) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ETV4
Gene ID: 2118
Uniprot ID: ETV4_HUMAN
Immunogen Region: 79-178
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 79-178 of human ETV4 (NP_001977.1).
Immunogen Sequence: PDFHSENLAFHSPTTRIKKE PQSPRTDPALSCSRKPPLPY HHGEQCLYSSAYDPPRQIAI KSPAPGALGQSPLQPFPRAE QRNFLRSSGTSQPHPGHGYL
Tissue Specificity Expressed in keratinocytes.
Post Translational Modifications Sumoylated.enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2.
Function Transcriptional activator. May play a role in keratinocyte differentiation. (Microbial infection) Binds to the enhancer of the adenovirus E1A gene and acts as a transcriptional activator.the core-binding sequence is 5'-ACGGAATGT-3'.
Protein Name Ets Translocations Variant 4
Adenovirus E1a Enhancer-Binding Protein
E1a-F
Polyomavirus Enhancer Activator 3 Homolog
Protein Pea3
Database Links Reactome: R-HSA-5687128
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Ets Translocations Variant 4 antibody
Anti-Adenovirus E1a Enhancer-Binding Protein antibody
Anti-E1a-F antibody
Anti-Polyomavirus Enhancer Activator 3 Homolog antibody
Anti-Protein Pea3 antibody
Anti-ETV4 antibody
Anti-E1AF antibody
Anti-PEA3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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