产品详情
简单介绍:
Anti-ETV6 antibody (223-272 aa) (STJ95965)
详情介绍:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Transcription factor ETV6 (223-272 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ETV6 |
Gene ID: | 2120 |
Uniprot ID: | ETV6_HUMAN |
Immunogen Region: | 223-272 aa |
Specificity: | TEL Polyclonal Antibody detects endogenous levels of TEL protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human Tel at the amino acid range 223-272 |
Post Translational Modifications | Phosphorylation of Ser-257 by MAPK14 (p38) inhibits ETV6 transcriptional repression. |
Function | Transcriptional repressor.binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation. |
Protein Name | Transcription Factor Etv6 Ets Translocations Variant 6 Ets-Related Protein Tel1 Tel |
Database Links | Reactome: R-HSA-9673768 Reactome: R-HSA-9703465 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Transcription Factor Etv6 antibody Anti-Ets Translocations Variant 6 antibody Anti-Ets-Related Protein Tel1 antibody Anti-Tel antibody Anti-ETV6 antibody Anti-TEL antibody Anti-TEL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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