Anti-CDCA2 antibody (511-560 aa) (STJ95418) STJ95418|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-CDCA2 antibody (511-560 aa) (STJ95418)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cell division cycle-associated protein 2 (511-560 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:5000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CDCA2
Gene ID:	157313
Uniprot ID:	CDCA2_HUMAN
Immunogen Region:	511-560 aa
Specificity:	Repo-Man Polyclonal Antibody detects endogenous levels of Repo-Man protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human CDCA2 at the amino acid range 511-560

Post Translational Modifications	Phosphorylated by CDK1. May regulate its subcellular locations.
Function	Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
Protein Name	Cell Division Cycle-Associated Protein 2 Recruits Pp1 Onto Mitotic Chromatin At Anaphase Protein Repo-Man
Cellular Localisation	Nucleus Excluded From The Nucleolus Present In Nucleoplasm Throughout The G1 S And G2 Stages Of The Cell Cycle During M Phase It Becomes Diffuse Throughout The Cell As The Nuclear Membrane Breaks Down And Faintly Accumulates Later On Metaphase Chromatin As The Cell Progresses To Anaphase It Accumulates On Chromatin
Alternative Antibody Names	Anti-Cell Division Cycle-Associated Protein 2 antibody Anti-Recruits Pp1 Onto Mitotic Chromatin At Anaphase Protein antibody Anti-Repo-Man antibody Anti-CDCA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-CDCA2 antibody (511-560 aa) (STJ95418)