Anti-CDCA7L antibody (1-300) (STJ117667) STJ117667|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-CDCA7L antibody (1-300) (STJ117667)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CDCA7L (1-300) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:200-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CDCA7L
Gene ID:	55536
Uniprot ID:	CDA7L_HUMAN
Immunogen Region:	1-300
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDCA7L (NP_061189.2).
Immunogen Sequence:	MELATRYQIPKEVADIFNAP SDDEEFVGFRDDVPMETLSS EESCDSFDSLESGKQQDVRF HSKYFTEELRRIFIEDTDSE TEDFAGFTQSDLNGKTNPEV MVVESDLSDDGKASLVSEEE EDEEEDKATPRRSRSRRSSI GLRVAFQFPTKKLANKPDKN SSSEQLFSSARLQNEKKTIL ERKKDCRQVIQREDSTSESE DDSRDESQESSDALLKRTMN IKENKAMLAQLLAELNSMP

Tissue Specificity	Ubiquitous. Overexpressed in medulloblastoma.
Post Translational Modifications	Phosphorylation increases its interaction with PSIP1.
Function	Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways.May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Protein Name	Cell Division Cycle-Associated 7-Like Protein Protein Jpo2 Transcription Factor Ram2
Cellular Localisation	Cytoplasm Nucleus Associates With Chromatin Translocates From Cytoplasm To Nucleus Under Dexamethasone Induction
Alternative Antibody Names	Anti-Cell Division Cycle-Associated 7-Like Protein antibody Anti-Protein Jpo2 antibody Anti-Transcription Factor Ram2 antibody Anti-CDCA7L antibody Anti-HR1 antibody Anti-JPO2 antibody Anti-R1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-CDCA7L antibody (1-300) (STJ117667)