Anti-CD222 antibody [MEM-238] (STJ16100179) STJ16100179-01|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-CD222 antibody [MEM-238] (STJ16100179)
產品型號：STJ16100179-01
產品廠商：ST john's laboratory
產品文檔：

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簡單介紹：

Anti-CD222 antibody [MEM-238] (STJ16100179)

詳情介紹：

Host:	Mouse
Applications:	FC/IP/WB
Reactivity:	Non-Human Primates/Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-CD222 is suitable for use in Flow Cytometry, Immunoprecipitation and Western Blot research applications.

Clonality:	Monoclonal
Clone ID:	MEM-238
Conjugation:	Unconjugated
Isotype:	IgG1
Formulation:	Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration:	1 mg/mL
Storage Instruction:	Store at 2-8°C upon receipt.

Immunogen:

Recombinant Vaccinia virus encoding CD222.

Background

CD222 (CIMPR, cation-independent mannose 6-phosphate receptor; IGF2 receptor) is a ubiquitously expressed 250 kDa transmembrane protein. No more than 10% of CD222 is present on the cell surface where it serves as a multifunctional receptor. Intracellular (major) fraction of CD222 is involved in transport of newly synthesized lysosomal enzymes modified by mannose 6-phosphate from Golgi apparatus to lysosomes. The cell surface CD222 binds and internalizes exogeneous mannose 6-phosphate-containing ligands. Importantly, CD222 is crutial for internalization and degradation of insulin-like growth factor 2, thus controling cell growth. CD222 also complexes CD87 (urokinase-type plasminogen-activator receptor) , plasminogen and latent TGF-beta, last but not least CD222 serves as a receptor for heparanase and even for Listeria.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-CD222 antibody [MEM-238] (STJ16100179)