產品詳情
簡單介紹:
Anti-CD24 antibody [M1/69] {AF647} (STJA0004096)
詳情介紹:
Host: | Rat |
Applications: | FC |
Reactivity: | Mouse |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: | Rat monoclonal antibody anti-Signal Transducer Cd24 |
Clonality: | Monoclonal |
Clone ID: | M1/69 |
Conjugation: | AF647 |
Isotype: | IgG2bk |
Formulation: | PBS with 0.05% Proclin300, 1% BSA |
Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Gene Symbol: | Cd24 |
Gene ID: | 12484 |
Uniprot ID: | CD24_MOUSE |
Tissue Specificity | In lymphoid, myeloid, and erythroid cells. |
Post Translational Modifications | The identity of the N- and O-linked polysaccharides is not reported in PubMed:1530634. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc. |
Function | May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity. |
Protein Name | Signal Transducer Cd24 Lymphocyte Antigen 52 Ly-52 M1/69-J11d Heat Stable Antigen Hsa Nectadrin R13-Ag X62 Heat Stable Antigen Cd Antigen Cd24 |
Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
Alternative Antibody Names | Anti-Signal Transducer Cd24 antibody Anti-Lymphocyte Antigen 52 antibody Anti-Ly-52 antibody Anti-M1/69-J11d Heat Stable Antigen antibody Anti-Hsa antibody Anti-Nectadrin antibody Anti-R13-Ag antibody Anti-X62 Heat Stable Antigen antibody Anti-Cd Antigen Cd24 antibody Anti-Cd24 antibody Anti-Cd24a antibody Anti-Ly-52 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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