Mouse CYP27B1 (Cytochrome P450 27B1) Sandwich ELISA Kit Ready-To-Use (STJE0014692) STJE0014692|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Mouse CYP27B1 (Cytochrome P450 27B1) Sandwich ELISA Kit Ready-To-Use (STJE0014692)
產品型號：STJE0014692
產品廠商：ST john's laboratory
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簡單介紹：

Mouse CYP27B1 (Cytochrome P450 27B1) Sandwich ELISA Kit Ready-To-Use (STJE0014692)

詳情介紹：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.214ng/mL
Detection Limit:	0.625-40ng/mL
Short Description:	This CYP27B1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Cyp27b1
Gene ID:	13115
Uniprot ID:	CP27B_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Kidney.
Post Translational Modifications
Function	A cytochrome P450 monooxygenase involved in vitamin D metabolism and in calcium and phosphorus homeostasis. Catalyzes the rate-limiting step in the activation of vitamin D in the kidney, namely the hydroxylation of 25-hydroxyvitamin D3/calcidiol at the C1-alpha position to form the hormonally active form of vitamin D3, 1alpha,25-dihydroxyvitamin D3/calcitriol that acts via the vitamin D receptor (VDR). Has 1-alpha-hydroxylase activity on vitamin D intermediates of the CYP24A1-mediated inactivation pathway. Converts 24R,25-dihydroxyvitamin D3/secalciferol to 1-alpha,24,25-trihydroxyvitamin D3, an active ligand of VDR. Also active on 25-hydroxyvitamin D2. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via FDXR/adrenodoxin reductase and FDX1/adrenodoxin.
Protein Name	25-Hydroxyvitamin D-1 Alpha Hydroxylase - Mitochondrial 25-Ohd-1 Alpha-Hydroxylase 25-Hydroxyvitamin D(3 1-Alpha-Hydroxylase Vd3 1a Hydroxylase Calcidiol 1-Monooxygenase Cytochrome P450 Subfamily Xxviib Polypeptide 1 Cytochrome P450c1 Alpha Cytochrome P450vd1-Alpha Cytochrome P450 27b1
Database Links	Reactome: R-MMU-196791 Reactome: -MMU-211916
Cellular Localisation	Mitochondrion Membrane
Alternative ELISA Names	25-Hydroxyvitamin D-1 Alpha Hydroxylase - Mitochondrial ELISA kit 25-Ohd-1 Alpha-Hydroxylase ELISA kit 25-Hydroxyvitamin D(3 1-Alpha-Hydroxylase ELISA kit Vd3 1a Hydroxylase ELISA kit Calcidiol 1-Monooxygenase ELISA kit Cytochrome P450 Subfamily Xxviib Polypeptide 1 ELISA kit Cytochrome P450c1 Alpha ELISA kit Cytochrome P450vd1-Alpha ELISA kit Cytochrome P450 27b1 ELISA kit Cyp27b1 ELISA kit Cyp27b ELISA kit Cyp40 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Mouse CYP27B1 (Cytochrome P450 27B1) Sandwich ELISA Kit Ready-To-Use (STJE0014692)