產品詳情
簡單介紹:
Anti-DDOST antibody (40-300) (STJ111545)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-DDOST (40-300) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IHC-P 1:100-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DDOST |
Gene ID: | 1650 |
Uniprot ID: | OST48_HUMAN |
Immunogen Region: | 40-300 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human DDOST (NP_005207.2). |
Immunogen Sequence: | VCASGPRTLVLLDNLNVRET HSLFFRSLKDRGFELTFKTA DDPSLSLIKYGEFLYDNLII FSPSVEDFGGNINVETISAF IDGGGSVLVAASSDIGDPLR ELGSECGIEFDEEKTAVIDH HNYDISDLGQHTLIVADTEN LLKAPTIVGKSSLNPILFRG VGMVADPDNPLVLDILTGSS TSYSFFPDKPITQYPHAVGK NTLLIAGLQARNNARVIFSG SLDFFSDSFFNSAVQKAAP |
Function | Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocations across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Required for the assembly of both SST3A- and SS3B-containing OST complexes. |
Protein Name | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 48 Kda Subunit Ddost 48 Kda Subunit Oligosaccharyl Transferase 48 Kda Subunit |
Database Links | Reactome: R-HSA-1799339 Reactome: R-HSA-446203 Reactome: R-HSA-6798695 Reactome: R-HSA-879415 Reactome: R-HSA-9694548 |
Cellular Localisation | Endoplasmic Reticulum Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 48 Kda Subunit antibody Anti-Ddost 48 Kda Subunit antibody Anti-Oligosaccharyl Transferase 48 Kda Subunit antibody Anti-DDOST antibody Anti-KIAA0115 antibody Anti-OST48 antibody Anti-OK antibody Anti-SW-cl.45 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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