產品詳情
簡單介紹:
Anti-DDX6 antibody (433-483) {FITC} (STJ500746)
詳情介紹:
Host: | Rabbit |
Applications: | DB/ELISA/IP/WB |
Reactivity: | Chicken/Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-DDX6 (433-483) is suitable for use in Dot Blot, ELISA, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | FITC |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.68-0.70 µg/µl |
Dilution Range: | WB: 1:500 DB: 1:4, 000 ELISA: 1:4, 000 IP: 1:150 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | DDX6 |
Gene ID: | 1656 |
Uniprot ID: | DDX6_HUMAN |
Immunogen Region: | 433-483 |
Immunogen: | Synthetic peptide taken within amino acid region 433-483 on probable ATP-dependent RNA helicase DDX6 protein. |
Tissue Specificity | Abundantly expressed in most tissues. |
Post Translational Modifications | Sumoylated. |
Function | Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. |
Protein Name | Probable Atp-Dependent Rna Helicase Ddx6 Atp-Dependent Rna Helicase P54 Dead Box Protein 6 Oncogene Rck |
Database Links | Reactome: R-HSA-430039 |
Cellular Localisation | Cytoplasm P-Body Nucleus Imported In The Nucleus Via Interaction With Eif4enif1/4e-T Via A Piggy-Back Mechanism Upon Cellular Stress Relocalizes To Stress Granules |
Alternative Antibody Names | Anti-Probable Atp-Dependent Rna Helicase Ddx6 antibody Anti-Atp-Dependent Rna Helicase P54 antibody Anti-Dead Box Protein 6 antibody Anti-Oncogene Rck antibody Anti-DDX6 antibody Anti-HLR2 antibody Anti-RCK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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