產品詳情
簡單介紹:
Anti-DDX6 antibody (STJA0008411)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Probable ATP-dependent RNA helicase DDX6 is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DDX6 |
Gene ID: | 1656 |
Uniprot ID: | DDX6_HUMAN |
Specificity: | This antibody detects endogenous levels of DDX6 at Human, Mouse |
Immunogen: | Synthesized peptide derived from human DDX6 |
Post Translational Modifications | Sumoylated. |
Function | Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. |
Protein Name | Probable Atp-Dependent Rna Helicase Ddx6 Atp-Dependent Rna Helicase P54 Dead Box Protein 6 Oncogene Rck |
Database Links | Reactome: R-HSA-430039 |
Cellular Localisation | Cytoplasm P-Body Nucleus Imported In The Nucleus Via Interaction With Eif4enif1/4e-T Via A Piggy-Back Mechanism Upon Cellular Stress Relocalizes To Stress Granules |
Alternative Antibody Names | Anti-Probable Atp-Dependent Rna Helicase Ddx6 antibody Anti-Atp-Dependent Rna Helicase P54 antibody Anti-Dead Box Protein 6 antibody Anti-Oncogene Rck antibody Anti-DDX6 antibody Anti-HLR2 antibody Anti-RCK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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