產品詳情
簡單介紹:
Anti-DEFA4 antibody (27-76 aa) (STJ92689)
詳情介紹:
Host: | Rabbit |
Applications: | IHC/IF/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Defensin alpha 4 (27-76 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DEFA4 |
Gene ID: | 1669 |
Uniprot ID: | DEF4_HUMAN |
Immunogen Region: | 27-76 aa |
Specificity: | Defensin Alpha 4 Polyclonal Antibody detects endogenous levels of Defensin Alpha 4 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human Defensin alpha4 at the amino acid range 27-76 |
Post Translational Modifications | The three-dimensional structure formed by the three intramolecular disulfide bridges is indispensable for effective bacterial killing. |
Function | Host-defense peptide that has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Exhibits antimicrobial activity against Gram-negative E.coli and E.aerogenes and Gram-positive S.faecalis, S.aureus and B.cereus and the yeast C.albicans (in vitro). Interacts with pathogenic surface proteins and toxins, such as HIV-1 surface protein gp120 and B.anthracis anthrax lethal factor lef. Protects blood cells against infection with HIV-1 (in vitro). Inhibits enzymatic activity of B.anthracis lef/anthrax lethal factor (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production (in vitro). |
Protein Name | Defensin Alpha 4 Corticostatin Hp-4 Hnp-4 Hp-4 Neutrophil Defensin 4 |
Database Links | Reactome: R-HSA-1461973 Reactome: R-HSA-1462054 Reactome: R-HSA-6798695 |
Cellular Localisation | Secreted Cytoplasmic Vesicle Secretory Vesicle Stored As Mature Peptide In Neutrophil Granules |
Alternative Antibody Names | Anti-Defensin Alpha 4 antibody Anti-Corticostatin Hp-4 antibody Anti-Hnp-4 antibody Anti-Hp-4 antibody Anti-Neutrophil Defensin 4 antibody Anti-DEFA4 antibody Anti-DEF4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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