Anti-DEFA4 antibody (40-97) (STJ11100311) STJ11100311|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-DEFA4 antibody (40-97) (STJ11100311)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-DEFA4 (40-97) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	DEFA4
Gene ID:	1669
Uniprot ID:	DEF4_HUMAN
Immunogen Region:	40-97
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 40-97 of human DEFA4 (NP_001916.1).
Immunogen Sequence:	QDISISFAWDKSSALQVSGS TRGMVCSCRLVFCRRTELRV GNCLIGGVSFTYCCTRVD

Tissue Specificity	Expressed in neutrophils (at protein level). Expressed in bone marrow.
Post Translational Modifications	The three-dimensional structure formed by the three intramolecular disulfide bridges is indispensable for effective bacterial killing.
Function	Host-defense peptide that has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Exhibits antimicrobial activity against Gram-negative E.coli and E.aerogenes and Gram-positive S.faecalis, S.aureus and B.cereus and the yeast C.albicans (in vitro). Interacts with pathogenic surface proteins and toxins, such as HIV-1 surface protein gp120 and B.anthracis anthrax lethal factor lef. Protects blood cells against infection with HIV-1 (in vitro). Inhibits enzymatic activity of B.anthracis lef/anthrax lethal factor (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production (in vitro).
Protein Name	Defensin Alpha 4 Corticostatin Hp-4 Hnp-4 Hp-4 Neutrophil Defensin 4
Database Links	Reactome: R-HSA-1461973 Reactome: R-HSA-1462054 Reactome: R-HSA-6798695
Cellular Localisation	Secreted Cytoplasmic Vesicle Secretory Vesicle Stored As Mature Peptide In Neutrophil Granules
Alternative Antibody Names	Anti-Defensin Alpha 4 antibody Anti-Corticostatin Hp-4 antibody Anti-Hnp-4 antibody Anti-Hp-4 antibody Anti-Neutrophil Defensin 4 antibody Anti-DEFA4 antibody Anti-DEF4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-DEFA4 antibody (40-97) (STJ11100311)