產品詳情
簡單介紹：
Anti-DGAT1 antibody [S5010RM] (STJ11105010)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-Diacylglycerol O-Acyltransferase 1 is suitable for use in Western Blot research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S5010RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DGAT1 |
| Gene ID: | 8694 |
| Uniprot ID: | DGAT1_HUMAN |
| Immunogen: | Recombinant protein of human DGAT1. |
| Function | Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Highly expressed in epithelial cells of the small intestine and its activity is essential for the absorption of dietary fats. In liver, plays a role in esterifying exogenous fatty acids to glycerol, and is required to synthesize fat for storage. Also present in female mammary glands, where it produces fat in the milk. May be involved in VLDL (very low density lipoprotein) assembly. In contrast to DGAT2 it is not essential for survival. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. Exhibits additional acyltransferase activities, includin acyl CoA:monoacylglycerol acyltransferase (MGAT), wax monoester and wax diester synthases. Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG). |
| Protein Name | Diacylglycerol O-Acyltransferase 1 Acat-Related Gene Product 1 Acyl-Coa Retinol O-Fatty-Acyltransferase Arat Retinol O-Fatty-Acyltransferase Diglyceride Acyltransferase |
| Database Links | Reactome: R-HSA-1482883 Reactome: R-HSA-6798695 Reactome: R-HSA-75109 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Diacylglycerol O-Acyltransferase 1 antibody Anti-Acat-Related Gene Product 1 antibody Anti-Acyl-Coa Retinol O-Fatty-Acyltransferase antibody Anti-Arat antibody Anti-Retinol O-Fatty-Acyltransferase antibody Anti-Diglyceride Acyltransferase antibody Anti-DGAT1 antibody Anti-AGRP1 antibody Anti-DGAT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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