Anti-DGKH antibody (771-820 aa) (STJ92701) STJ92701|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-DGKH antibody (771-820 aa) (STJ92701)

詳情介紹：

Host:	Rabbit
Applications:	IHC/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Diacylglycerol kinase eta (771-820 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	DGKH
Gene ID:	160851
Uniprot ID:	DGKH_HUMAN
Immunogen Region:	771-820 aa
Specificity:	DGK-Eta Polyclonal Antibody detects endogenous levels of DGK-Eta protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human DGKH at the amino acid range 771-820

Post Translational Modifications	Phosphorylated. Phosphorylation does not inhibit catalytic activity.
Function	Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.
Protein Name	Diacylglycerol Kinase Eta Dag Kinase Eta Diglyceride Kinase Eta Dgk-Eta
Database Links	Reactome: R-HSA-114508
Cellular Localisation	Cytoplasm Cell Membrane Translocated From The Cytoplasm To Endosomes In Response To Stress Stimuli Isoform 2 Is Rapidly Relocated Back To The Cytoplasm Upon Removal Of Stress Stimuli Whereas Isoform 1 Exhibits Sustained Endosomal Association Translocates From The Cytoplasm To The Cell Membrane In The Presence Of Active Gtp-Bound Form Of Hras
Alternative Antibody Names	Anti-Diacylglycerol Kinase Eta antibody Anti-Dag Kinase Eta antibody Anti-Diglyceride Kinase Eta antibody Anti-Dgk-Eta antibody Anti-DGKH antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-DGKH antibody (771-820 aa) (STJ92701)