產品詳情
簡單介紹：
Anti-DHCR7 antibody (346-475) (STJ110352)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-DHCR7 (346-475) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DHCR7 |
| Gene ID: | 1717 |
| Uniprot ID: | DHCR7_HUMAN |
| Immunogen Region: | 346-475 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 346-475 of human DHCR7 (NP_001351.2). |
| Immunogen Sequence: | VGYYIFRVANHQKDLFRRTD GRCLIWGRKPKVIECSYTSA DGQRHHSKLLVSGFWGVARH FNYVGDLMGSLAYCLACGGG HLLPYFYIIYMAILLTHRCL RDEHRCASKYGRDWERYTAA VPYRLLPGIF |
| Tissue Specificity | Widely expressed. Most abundant in adrenal gland, liver, testis, and brain. |
| Function | 7-dehydrocholesterol reductase of the cholesterol biosesynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway. |
| Protein Name | 7-Dehydrocholesterol Reductase 7-Dhc Reductase Delta7-Sterol Reductase Sterol Delta(7-Reductase Sterol Reductase Sr-2 |
| Database Links | Reactome: R-HSA-2426168 Reactome: R-HSA-6807047 Reactome: R-HSA-6807062 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-7-Dehydrocholesterol Reductase antibody Anti-7-Dhc Reductase antibody Anti-Delta7-Sterol Reductase antibody Anti-Sterol Delta(7-Reductase antibody Anti-Sterol Reductase Sr-2 antibody Anti-DHCR7 antibody Anti-D7SR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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