產品詳情
簡單介紹:
Mouse GLS (Glutaminase) Sandwich ELISA Kit (STJE0009204)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.117ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This GLS Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Gls |
Gene ID: | 14660 |
Uniprot ID: | GLSK_MOUSE |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Synthesized as a 74-kDa cytosolic precursor which is proteolytically processed by the mitochondrial-processing peptidase (MPP) via a 72-kDa intermediate to yield the mature mitochondrial 68- and 65-kDa subunits. |
Function | Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain. |
Protein Name | Glutaminase Kidney Isoform - Mitochondrial Gls Cleaved Into - Glutaminase Kidney Isoform - Mitochondrial 68 Kda Chain - Glutaminase Kidney Isoform - Mitochondrial 65 Kda Chain |
Database Links | Reactome: R-MMU-210500 Reactome: -MMU-5628897 Reactome: -MMU-8964539 |
Cellular Localisation | Isoform 1: Mitochondrion Cytoplasm Cytosol The 74-Kda Cytosolic Precursor Is Translocated Into The Mitochondria And Processed Via A 72-Kda Intermediate To Yield The Mature 68- And 65-Kda Subunits Isoform 2: Mitochondrion Glutaminase Kidney Isoform Mitochondrial 68 Kda Chain: Mitochondrion Matrix Produced By The Proteolytic Processing Of The 74-Kda Cytosolic Precursor Mitochondrial 65 Kda Chain: Mitochondrion Matrix |
Alternative ELISA Names | Glutaminase Kidney Isoform - Mitochondrial ELISA kit Gls Cleaved Into - Glutaminase Kidney Isoform - Mitochondrial 68 Kda Chain - Glutaminase Kidney Isoform - Mitochondrial 65 Kda Chain ELISA kit Gls ELISA kit Gls1 ELISA kit Kiaa0838 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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