產品詳情
簡單介紹:
Anti-DIO2 antibody (STJ192992)
詳情介紹:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Type II iodothyronine deiodinase is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DIO2 |
Gene ID: | 1734 |
Uniprot ID: | IOD2_HUMAN |
Specificity: | IOD2 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from part of the human protein |
Post Translational Modifications | Ubiquitinated by MARCHF6, leading to its degradation by the proteasome. Deubiquitinated by USP20 and USP33. |
Function | Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development. |
Protein Name | Type Ii Iodothyronine Deiodinase 5dii Dioii Type 2 Di Type-Ii 5'-Deiodinase |
Database Links | Reactome: R-HSA-350864 |
Cellular Localisation | Membrane Single-Pass Membrane Protein |
Alternative Antibody Names | Anti-Type Ii Iodothyronine Deiodinase antibody Anti-5dii antibody Anti-Dioii antibody Anti-Type 2 Di antibody Anti-Type-Ii 5'-Deiodinase antibody Anti-DIO2 antibody Anti-ITDI2 antibody Anti-TXDI2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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