產品詳情
簡單介紹：
Anti-DNAJC3 antibody (80-160 aa) (STJ190215)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-DnaJ homolog subfamily C member 3 (80-160 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNAJC3 |
| Gene ID: | 5611 |
| Uniprot ID: | DNJC3_HUMAN |
| Immunogen Region: | 80-160 aa |
| Specificity: | DNJC3 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 80-160 |
| Function | Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity. |
| Protein Name | Dnaj Homolog Subfamily C Member 3 Endoplasmic Reticulum Dna J Domain-Containing Protein 6 Er-Resident Protein Erdj6 Erdj6 Interferon-Induced - Double-Stranded Rna-Activated Protein Kinase Inhibitor Protein Kinase Inhibitor Of 58 Kda Protein Kinase Inhibitor P58 |
| Database Links | Reactome: R-HSA-192823 Reactome: R-HSA-381038 Reactome: R-HSA-381426 Reactome: R-HSA-6798695 Reactome: R-HSA-8957275 |
| Cellular Localisation | Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 3 antibody Anti-Endoplasmic Reticulum Dna J Domain-Containing Protein 6 antibody Anti-Er-Resident Protein Erdj6 antibody Anti-Erdj6 antibody Anti-Interferon-Induced - Double-Stranded Rna-Activated Protein Kinase Inhibitor antibody Anti-Protein Kinase Inhibitor Of 58 Kda antibody Anti-Protein Kinase Inhibitor P58 antibody Anti-DNAJC3 antibody Anti-P58IPK antibody Anti-PRKRI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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