Anti-DNAJC5 antibody (131-180 aa) (STJ92500) STJ92500|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-DNAJC5 antibody (131-180 aa) (STJ92500)

詳情介紹：

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-DnaJ homolog subfamily C member 5 (131-180 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	DNAJC5
Gene ID:	80331
Uniprot ID:	DNJC5_HUMAN
Immunogen Region:	131-180 aa
Specificity:	CSP Polyclonal Antibody detects endogenous levels of CSP protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human DNAJC5 at the amino acid range 131-180

Post Translational Modifications	Ser-10 phosphorylation induces an order-to-disorder transition triggering the interaction with Lys-58. This conformational switch modulates DNAJC5's cellular functions by reducing binding to syntaxin and synaptogamin without altering HSC70 interactions. Palmitoylated. Could be palmitoylated by DHHC3, DHHC7, DHHC15 and DHHC17. Palmitoylation occurs probably in the cysteine-rich domain and regulates DNAJC5 membrane attachment.
Function	Acts as a general chaperone in regulated exocytosis. Acts as a co-chaperone for the SNARE protein SNAP-25. Involved in the calcium-mediated control of a late stage of exocytosis. May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings.
Protein Name	Dnaj Homolog Subfamily C Member 5 Ceroid-Lipofuscinosis Neuronal Protein 4 Cysteine String Protein Csp
Database Links	Reactome: R-HSA-6798695 Reactome: R-HSA-888590 Reactome: R-HSA-9662360
Cellular Localisation	Cytoplasm Cytosol Membrane Lipid-Anchor Cytoplasmic Vesicle Secretory Vesicle Chromaffin Granule Membrane Melanosome Cell Membrane The Association With Membranes Is Regulated By Palmitoylation Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names	Anti-Dnaj Homolog Subfamily C Member 5 antibody Anti-Ceroid-Lipofuscinosis Neuronal Protein 4 antibody Anti-Cysteine String Protein antibody Anti-Csp antibody Anti-DNAJC5 antibody Anti-CLN4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-DNAJC5 antibody (131-180 aa) (STJ92500)