產品詳情
簡單介紹:
Anti-DNAJC7 antibody (230-380) (STJ23402)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-DNAJC7 (230-380) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:1000-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DNAJC7 |
Gene ID: | 7266 |
Uniprot ID: | DNJC7_HUMAN |
Immunogen Region: | 230-380 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human DNAJC7 (NP_003306.3). |
Immunogen Sequence: | VQFFVQALRMAPDHEKACIA CRNAKALKAKKEDGNKAFKE GNYKLAYELYTEALGIDPNN IKTNAKLYCNRGTVNSKLRK LDDAIEDCTNAVKLDDTYIK AYLRRAQCYMDTEQYEEAVR DYEKVYQTEKTKEHKQLLKN AQLELKKSKRK |
Function | Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm. |
Protein Name | Dnaj Homolog Subfamily C Member 7 Tetratricopeptide Repeat Protein 2 Tpr Repeat Protein 2 |
Database Links | Reactome: R-HSA-3371453 |
Cellular Localisation | Cytoplasm Nucleus Cytoskeleton Colocalizes With Nr1i3 To Microtubules |
Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 7 antibody Anti-Tetratricopeptide Repeat Protein 2 antibody Anti-Tpr Repeat Protein 2 antibody Anti-DNAJC7 antibody Anti-TPR2 antibody Anti-TTC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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